Cell Energy Metabolism and Hyaluronan Synthesis
نویسندگان
چکیده
منابع مشابه
Energy Metabolism and T-cell-mediated Cytolysis
The destruction of appropriate target cells by cytolytic thymus-derived lymphocytes (CTL) 1 is an active energy-requiring phenomenon (1-3). In the accompanying paper (4), we presented evidence that T-cell-mediated cytolysis could be supported by either oxidative or glycolytic energy pathways and was in general strongly inhibited only in those situations in which both respiration and glycolysis ...
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The tissue homing of malignant hematic cells has both diagnostic and pathogenetic importance. Although such homing is incompletely understood, it generally involves cell adhesion and migration mediated by a number of adhesion receptors and cytokines. In this article, the potential importance of hyaluronan (HA) is examined for the tissue homing of hairy cells (HCs) in hairy cell leukemia (HCL). ...
متن کاملIntestinal triacylglycerol synthesis in fat absorption and systemic energy metabolism.
The intestine plays a prominent role in the biosynthesis of triacylglycerol (triglyceride; TAG). Digested dietary TAG is repackaged in the intestine to form the hydrophobic core of chylomicrons, which deliver metabolic fuels, essential fatty acids, and other lipid-soluble nutrients to the peripheral tissues. By controlling the flux of dietary fat into the circulation, intestinal TAG synthesis c...
متن کاملChain Gangs: New Aspects of Hyaluronan Metabolism
Hyaluronan is a matrix polymer prominent in tissues undergoing rapid growth, development, and repair, in embryology and during malignant progression. It reaches 10(7) Daltons in size but also exists in fragmented forms with size-specific actions. It has intracellular forms whose functions are less well known. Hyaluronan occurs in all vertebrate tissues with 50% present in skin. Hyaluronan provi...
متن کاملInhibition of hyaluronan synthesis accelerates murine atherosclerosis: novel insights into the role of hyaluronan synthesis.
BACKGROUND Hyaluronan is thought to mediate neointimal hyperplasia but also vasoprotection as an integral component of the endothelial glycocalyx. The present study addressed for the first time the effects of long-term pharmacological inhibition of hyaluronan synthesis on vascular function and atherosclerosis. METHODS AND RESULTS Four-week-old apolipoprotein E-deficient mice on a Western diet...
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ژورنال
عنوان ژورنال: Journal of Histochemistry & Cytochemistry
سال: 2020
ISSN: 0022-1554,1551-5044
DOI: 10.1369/0022155420929772